Yea me! I just upgraded from Word Press 2.2 to 2.9, which is a pretty substantial upgrade to [knock on wood] not experience any issues with the upgrade process.
For those of you that are interested, I followed these fairly simple upgrade instructions. Of course, like a good company man, I did a backup, made sure I had my shell access working, and then started the ftp for the updated files.
I have only done initial tests, but everything seems to be working correctly, included the current theme. I figured that puppy was going to die a painful upgrade death.
It looks like a couple of my plugins may not be working, but no worries, as I was planning to add some new ones anyway.
You may see some more wackiness and the like as I continue some improvements over the weekend, but the major stuff is out of the way. Happy days!